FIP200 antibody

Catalog No. ABIN375311

The Rabbit Polyclonal anti-FIP200 antibody is suitable to detect FIP200 in samples from Mouse. It has been validated for WB, ELISA and ICC.

Quick Overview for FIP200 antibody (ABIN375311)

Target: FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FIP200 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Product Details anti-FIP200 Antibody

Specificity: Reacts with mouse Rb1cc1

Cross-Reactivity (Details): Cross reacts with Rb1cc1 proteins from human and other species

Purification: Antiserum

Immunogen: Synthetic peptide derived from an internal domain of mouse Rb1cc1

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC1:50 - 1:500 WB1:200 - 1:2 000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for FIP200

Target: FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

Alternative Name: RB1-Inducible Coiled-Coil Protein 1

Background: Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a novel mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.

Gene ID: 12421

UniProt: Q9ESK9

Pathways: Regulation of Cell Size, Autophagy