FIP200 antibody
Quick Overview for FIP200 antibody (ABIN375311)
Target
See all FIP200 (RB1CC1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Reacts with mouse Rb1cc1
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Cross-Reactivity (Details)
- Cross reacts with Rb1cc1 proteins from human and other species
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Purification
- Antiserum
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Immunogen
- Synthetic peptide derived from an internal domain of mouse Rb1cc1
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Isotype
- IgG
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Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC1:50 - 1:500 WB1:200 - 1:2 000 -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Must be reconstituted in distilled water.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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Expiry Date
- 24 months
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- FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
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Alternative Name
- RB1-Inducible Coiled-Coil Protein 1
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Background
- Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a novel mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.
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Gene ID
- 12421
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UniProt
- Q9ESK9
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Pathways
- Regulation of Cell Size, Autophagy
Target
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