Fascin antibody (N-Term)

Catalog No. ABIN375367

This Rabbit Polyclonal antibody specifically detects Fascin in WB, IHC, ELISA and ICC. It exhibits reactivity toward Human.

Quick Overview for Fascin antibody (N-Term) (ABIN375367)

Target: Fascin (FSCN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fascin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Product Details anti-Fascin Antibody

Binding Specificity: N-Term

Specificity: Reacts with 50 kDa FSCN1 with a phosphorylation at Serine 39

Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): May cross react with FSCN1 phospho-proteins from rat, mouse and other species due to homology sequences.

Purification: Antiserum

Immunogen: Synthetic peptide derived from Nter domain of human FSCN1 containing phosphorserine at position 39

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC(1:100 - 1:1000) WB(1:500 - 1:2000)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for Fascin

Target: Fascin (FSCN1)

Alternative Name: Fascin

Background: Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. Phosphorylation on Ser-39 inhibits the actin-binding ability of fascin.

Gene ID: 6624

UniProt: Q16658