CD8 antibody (PE-Cy5.5)

Catalog No. ABIN376615

This Mouse Monoclonal antibody specifically detects CD8 in FACS. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for CD8 antibody (PE-Cy5.5) (ABIN376615)

Target: CD8

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD8 antibody is conjugated to PE-Cy5.5

Application: Flow Cytometry (FACS)

Clone: RFT8

Product Details anti-CD8 Antibody (PE-Cy5.5)

Specificity: Human CD8, Mr 33 kDa

Characteristics: Mouse Anti-Human CD8-PE/CY5.5

Purification: Purified

Immunogen: Thymocyte and E-rosetted lymphocytes

Isotype: IgG1

Application Details

Application Notes:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , Depletion - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, PE/TXRD, APC, SPRD, CY5, PE/CY5.5, 10 L/106 cells PE/CY7, APC/CY5.5, APC/CY7, PACBLU, AF488, AF647, and AF700 conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Restrictions: For Research Use only

Handling

Buffer: 100 tests in 1.0 mL PBS/Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

References for anti-CD8 antibody (PE-Cy5.5) (ABIN376615)

Kim, Kim, Shin, Jung, Choi, Jun: "Expression patterns of programmed death-1 and programmed death-1 ligand-1 on T cells in gastric cancer." in: Oncology letters, Vol. 18, Issue 3, pp. 2661-2669, (2019) (PubMed).

Yuan, Kang, Daharsh, Fan, Li: "SIVcpz closely related to the ancestral HIV-1 is less or non-pathogenic to humans in a hu-BLT mouse model." in: Emerging microbes & infections, Vol. 7, Issue 1, pp. 59, (2018) (PubMed).

Target Details for CD8

Target: CD8

Alternative Name: CD8

Background: CD8 is a 32 kDa transmembrane glycoprotein expressed as either a CD8 αα homodimer or CD8 αβ heterodimer. It is expressed on the 'cytotoxic/suppressor' subpopulation of peripheral T cells. CD8 functions primarily as a coreceptor with MHC Class I-restricted TCR's in antigen recognition.