Cofilin antibody (pTyr140, Ser156)

Catalog No. ABIN377420

The Sheep Polyclonal anti-Cofilin antibody has been validated for WB and IHC. It is suitable to detect Cofilin in samples from Human, Mouse and Rat.

Quick Overview for Cofilin antibody (pTyr140, Ser156) (ABIN377420)

Target: Cofilin (CFL1) (Cofilin 1 (CFL1))

Reactivity: Human, Mouse, Rat

Host: Sheep

Clonality: Polyclonal

Conjugate: This Cofilin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Cofilin Antibody

Binding Specificity: pTyr140, Ser156

Specificity: Specific for Cofilin-1.

Purification: Purified

Immunogen: Synthetic peptide from the phospho Y140 & S156 of human Cofilin-1 (Cofilin, non-muscle isoform) conjugated to an immunogenic carrier protein. The antigen is homologous in rat, mouse and monkey.

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, WB

Usage: IHC: Antigen retrieval is essential for use on paraffin sections.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile water

Concentration: Lot specific

Buffer: Lyophilized. Centrifuge to remove any insoluble material

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain lyophilized and reconstituted antibodies at -20°C for long term storage and at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze/thaw cycles.

Target Details for Cofilin

Target: Cofilin (CFL1) (Cofilin 1 (CFL1))

Alternative Name: CFL1 / Cofilin

Background: Name/Gene ID: CFL1

Synonyms: CFL1, 18 kDa phosphoprotein, Cofilin, CFL, Cofilin 1 (non-muscle), Cofilin, non-muscle isoform, p18

Gene ID: 1072

UniProt: P23528

Pathways: Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events