CD163 antibody

Catalog No. ABIN379942

This Mouse Monoclonal antibody specifically detects CD163 in IHC and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for CD163 antibody (ABIN379942)

Target: CD163

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD163 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: RM3-1

Product Details anti-CD163 Antibody

Specificity: The antigen is CD163, the epitope has not been further characterized. Antigen distribution: Isolated cells: Monocytes, particularly after dexamethasone treatment or after 2-5 days in culture. Does not react with lymphocytes, granulocytes or platelets. Tissue sections: Positive staining can be observed in the skin (histiocytes), gut, Kupffer cells, few alveolar macrophages, a major population of macrophages in the placenta, varying degrees of macrophages in inflamed tissues, including tumorous tissue depending on the inflammatory stage. Red pulp, but not white pulp macrophages of the spleen, and cortical macrophages of the thymus are detected. Macrophages in the synovialis of patients with rheumatoid arthritis. In alveolar macrophages and in Kupffer cells a double staining can be observed with monoclonal antibody 25F9 which is not the case in other tissues. Specificity: Human: monocytes and macrophages. Other: positive in monkey, negative in pig, rabbit and guinea pig.

Purification: Affinity purified

Immunogen: Human monocytes

Type of Immunogen: Cells

Application Details

Application Notes: Approved: IHC, IHC-Fr (1:100)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 0.5 mL distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.01 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C.

Target Details for CD163

Target: CD163

Alternative Name: CD163

Background: Name/Gene ID: CD163

Synonyms: CD163, CD163 antigen, Macrophage-associated antigen, M130, CD163 Molecule, Hemoglobin scavenger receptor, MM130

Gene ID: 9332

UniProt: Q86VB7