CD93 antibody (Biotin)

Catalog No. ABIN379954

This Mouse Monoclonal antibody specifically detects CD93 in IHC and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for CD93 antibody (Biotin) (ABIN379954)

Target: CD93

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD93 antibody is conjugated to Biotin

Application: Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: X-2

Product Details anti-CD93 Antibody (Biotin)

Specificity: The antigen has been assigned to the CDw93 cluster, the epitope has not been further characterized. Antigen distribution: Isolated cells: Positive with all granulocytes, with staining increasing transiently upon maturation. Antigen expression is increased by TNFa, GM-CSF, (fMLP) treatment. No effect on superoxide production by binding to neutrophils has been noted. PMA stimulation causes down regulation of the antigen. Positive with monocytes following fMLP, TNF, GM-CSF treatment. Antigen expression decreases on cultured monocytes. Positive on AML cases with monocytic component. Positive on cell lines HL-60, Namalva, K562, THP-1, U937, negative on HMC-1 (human mast cell line). Tissue sections: Monoclonal antibody X-2 stains epitheloid cells and Rosai-Dorfman cells and most endothelial cells in the synovial membrane of RA patients. Specificity: Human: granulocytes, monocytes, endothelial cells (main cellular reactivity). Other: not tested.

Purification: Affinity purified

Immunogen: Human monocytes

Type of Immunogen: Cells

Application Details

Application Notes: Approved: IHC, IHC-Fr (1:400)

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 0.5 mL distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.01 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C.

Target Details for CD93

Target: CD93

Alternative Name: C1qRP / CD93

Background: Name/Gene ID: CD93

Synonyms: CD93, C1qR(P), C1qRP, CD93 Molecule, DJ737E23.1, ECSM3, C1q receptor 1, C1q/MBL/SPA receptor, C1qR, C1QR1, CD93 antigen, MXRA4

Gene ID: 22918

UniProt: Q9NPY3