KDM2A antibody (AA 500-527)

Catalog No. ABIN387896

The Rabbit Polyclonal anti-KDM2A antibody has been validated for WB and IHC (p). It is suitable to detect KDM2A in samples from Human.

Quick Overview for KDM2A antibody (AA 500-527) (ABIN387896)

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB14392

Product Details anti-KDM2A Antibody

Binding Specificity: AA 500-527

Predicted Reactivity: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This JHDM1a/FBXL11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 500-527 amino acids from the Central region of human JHDM1a/FBXL11.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for KDM2A

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Alternative Name: JHDM1a/FBXL11

Background: JHDM1a/FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats.

Molecular Weight: 132793

Gene ID: 22992

NCBI Accession: NP_001243334, NP_036440

UniProt: Q9Y2K7

Pathways: Warburg Effect