KAT5 antibody (N-Term)

Catalog No. ABIN387933

This anti-KAT5 antibody is a Rabbit Polyclonal antibody detecting KAT5 in WB. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for KAT5 antibody (N-Term) (ABIN387933)

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT5 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB05776

Product Details anti-KAT5 Antibody

Binding Specificity: AA 33-64, N-Term

Predicted Reactivity: M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This KAT5 / Tip60/HTATIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-64 amino acids from the N-terminal region of human KAT5 / Tip60/HTATIP.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-KAT5 antibody (ABIN387933)

Yamagata, Kitabayashi: "Sirt1 physically interacts with Tip60 and negatively regulates Tip60-mediated acetylation of H2AX." in: Biochemical and biophysical research communications, Vol. 390, Issue 4, pp. 1355-60, (2009) (PubMed).

Target Details for KAT5

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Alternative Name: KAT5 / Tip60/HTATIP

Background: HTATIP belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.

Molecular Weight: 58582

Gene ID: 10524

NCBI Accession: NP_001193762, NP_006379, NP_874368, NP_874369

UniProt: Q92993

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway