BMP1 antibody (C-Term)

Catalog No. ABIN388451

The Rabbit Polyclonal anti-BMP1 antibody has been validated for WB and IHC (p). It is suitable to detect BMP1 in samples from Mouse.

Quick Overview for BMP1 antibody (C-Term) (ABIN388451)

Target: BMP1 (Bone Morphogenetic Protein 1 (BMP1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB1853-1854

Product Details anti-BMP1 Antibody

Binding Specificity: AA 957-986, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Bmp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 957-986 amino acids from the C-terminal region of human Bmp1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for BMP1

Target: BMP1 (Bone Morphogenetic Protein 1 (BMP1))

Alternative Name: Bmp1

Background: The BMP1 locus encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, BMP1 encodes a protein that is not closely related to other known growth factors. BMP1 protein and procollagen C proteinase (PCP), a secreted metalloprotease requiring calcium and needed for cartilage and bone formation, are identical. PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I, II, and III and its activity is increased by the procollagen C-endopeptidase enhancer protein. The BMP1 gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.

Molecular Weight: 111249

Gene ID: 649

NCBI Accession: NP_001190, NP_006120

UniProt: P13497

Pathways: Lipid Metabolism