Endoribonuclease Dcr-1 (Dcr-1) (AA 1068-1097) antibody
Quick Overview for Endoribonuclease Dcr-1 (Dcr-1) (AA 1068-1097) antibody (ABIN388686)
Target
See all Endoribonuclease Dcr-1 (Dcr-1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1068-1097
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This Dcr-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1068-1097 amino acids of CAEEL Dcr-1.
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Isotype
- Ig Fraction
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Expiry Date
- 6 months
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- Endoribonuclease Dcr-1 (Dcr-1)
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Alternative Name
- Dcr-1
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Background
- The Dcr-1 gene encodes a bidentate ribonuclease that is homologous to E. coli RNAse III. Dcr-1 is required both for RNA interference and for synthesis of small developmental RNAs. Dcr-1 interacts in vivo with RDE-4, a double-stranded RNA (dsRNA) binding protein required for RNAi that interacts with trigger dsRNAs and may function to deliver dsRNAs to Dcr-1 for endonucleolytic processing.
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Molecular Weight
- 218423
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Gene ID
- 176138
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NCBI Accession
- NP_498761
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UniProt
- P34529
Target
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