tau antibody (C-Term)

Catalog No. ABIN388782

This anti-tau antibody is a Rabbit Polyclonal antibody detecting tau in WB, IF and IHC (p). Suitable for Human, Mouse, Rat and Cynomolgus.

Quick Overview for tau antibody (C-Term) (ABIN388782)

Target: tau (tau Protein)

Reactivity: Human, Mouse, Rat, Cynomolgus

Host: Rabbit

Clonality: Polyclonal

Conjugate: This tau antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB2883

Product Details anti-tau Antibody

Binding Specificity: AA 677-707, C-Term

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TAU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 677-707 amino acids from the C-terminal region of human TAU.

Isotype: IgG

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. WB: 1:2000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for tau

Target: tau (tau Protein)

Alternative Name: tau

Background: The microtubule-associated protein tau (MAPT) gene transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations result in several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Molecular Weight: 78928

Gene ID: 4137

NCBI Accession: NP_001116538, NP_001116539, NP_001190181, NP_005901, NP_058518, NP_058519, NP_058525

UniProt: P10636