ART1 antibody (N-Term)

Catalog No. ABIN389008

This Rabbit Polyclonal antibody specifically detects ART1 in WB. It exhibits reactivity toward Human and Mouse and has been mentioned in 2+ publications.

Quick Overview for ART1 antibody (N-Term) (ABIN389008)

Target: ART1 (ADP-Ribosyltransferase 1 (ART1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ART1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB4939

Product Details anti-ART1 Antibody

Binding Specificity: AA 14-43, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ART1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human ART1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-ART1 antibody (ABIN389008)

Song, Jin, Zhao, Tang, Wang, Li, Xiao, Li, Li, Lin, Chen, Kuang: "Regulation of the RhoA/ROCK/AKT/β-catenin pathway by arginine-specific ADP-ribosytransferases 1 promotes migration and epithelial-mesenchymal transition in colon carcinoma." in: International journal of oncology, Vol. 49, Issue 2, pp. 646-56, (2017) (PubMed).

Yang, Xiao, Li, Tang, Wang: "Arginine ADP-ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway." in: International journal of molecular medicine, Vol. 37, Issue 3, pp. 734-42, (2016) (PubMed).

Target Details for ART1

Target: ART1 (ADP-Ribosyltransferase 1 (ART1))

Alternative Name: ART1

Background: ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence of ART1 consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins.

Molecular Weight: 36335

Gene ID: 417

NCBI Accession: NP_004305

UniProt: P52961