GCNT1 antibody (AA 88-117)

Catalog No. ABIN389033

The Rabbit Polyclonal anti-GCNT1 antibody is suitable to detect GCNT1 in samples from Human and Mouse. It has been validated for WB and IHC (p).

Quick Overview for GCNT1 antibody (AA 88-117) (ABIN389033)

Target: GCNT1 (Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCNT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB4836

Product Details anti-GCNT1 Antibody

Binding Specificity: AA 88-117

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This GCNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human GCNT1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for GCNT1

Target: GCNT1 (Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1))

Alternative Name: GCNT1

Background: Glycosylation is one of the most universal but at the same time complex protein modifications. Modification with sugar moeties can be both co- translational and post- translational, occurring in the endoplasmatic reticulum and golgi. Three different forms of glycosylation can be distinguished: N-linked oligosaccharides, O-linked oligosaccharides and glycosyl- phosphatidylinositol (GPI-) anchors. Glycosylation results in thousands of distinct, bioactive glycoproteins resident throughout the cell that strongly determine protein-protein, carbohydrate-protein, membrane, and adhesion properties. Diseases associated with glycosylation defects include Congenital disorders of glycosylation, (CDG), also known as carbohydrate deficient glycoprotein syndromes, and diseases associated with advanced aging.

Molecular Weight: 49799

Gene ID: 2650

NCBI Accession: NP_001091102, NP_001091103, NP_001091104, NP_001091105, NP_001481

UniProt: Q02742