POLR1C antibody (C-Term)

Catalog No. ABIN389351

The Rabbit Polyclonal anti-POLR1C antibody is suitable to detect POLR1C in samples from Human and Mouse. It has been validated for WB and IHC (p).

Quick Overview for POLR1C antibody (C-Term) (ABIN389351)

Target: POLR1C (Polymerase (RNA) I Polypeptide C, 30kDa (POLR1C))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR1C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB17524

Product Details anti-POLR1C Antibody

Binding Specificity: AA 319-346, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This POLR1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-346 amino acids from the C-terminal region of human POLR1C.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for POLR1C

Target: POLR1C (Polymerase (RNA) I Polypeptide C, 30kDa (POLR1C))

Alternative Name: POLR1C

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft.

Molecular Weight: 39250

Gene ID: 9533

NCBI Accession: NP_976035

UniProt: O15160