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EGFR antibody (pTyr1016)

EGFR Reactivity: Human WB, DB Host: Rabbit Polyclonal RB11166 unconjugated
Catalog No. ABIN2839735
  • Target See all EGFR Antibodies
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    Binding Specificity
    • 39
    • 38
    • 31
    • 31
    • 30
    • 27
    • 27
    • 26
    • 24
    • 22
    • 19
    • 18
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 11
    • 11
    • 10
    • 9
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    pTyr1016
    Reactivity
    • 749
    • 296
    • 283
    • 25
    • 25
    • 24
    • 19
    • 14
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 580
    • 166
    • 14
    • 13
    • 5
    • 4
    • 1
    • 1
    Rabbit
    Clonality
    • 542
    • 237
    • 2
    Polyclonal
    Conjugate
    • 411
    • 58
    • 29
    • 22
    • 19
    • 17
    • 16
    • 16
    • 16
    • 16
    • 16
    • 11
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 8
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EGFR antibody is un-conjugated
    Application
    • 534
    • 250
    • 149
    • 147
    • 125
    • 102
    • 98
    • 93
    • 82
    • 46
    • 37
    • 34
    • 34
    • 18
    • 11
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Dot Blot (DB)
    Predicted Reactivity
    M
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This EGFR Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1016 of human EGFR.
    Clone
    RB11166
    Isotype
    Ig Fraction
    Top Product
    Discover our top product EGFR Primary Antibody
  • Application Notes
    WB: 1:8000. DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    Alternative Name
    EGFR (EGFR Products)
    Background
    Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma. EGFR is a receptor for EGF, but also for other members of the EGF family, including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. It is involved in the control of cell growth and differentiation.
    Molecular Weight
    134277
    Gene ID
    1956
    NCBI Accession
    NP_005219, NP_958439, NP_958440, NP_958441
    UniProt
    P00533
    Pathways
    NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
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