GIT1 antibody (pTyr554)

Catalog No. ABIN389936

The Rabbit Polyclonal anti-GIT1 antibody is suitable to detect GIT1 in samples from Human. It has been validated for DB.

Quick Overview for GIT1 antibody (pTyr554) (ABIN389936)

Target: GIT1

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIT1 antibody is un-conjugated

Application: Dot Blot (DB)

Clone: RB15351

Product Details anti-GIT1 Antibody

Binding Specificity: pTyr554

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GIT1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y554 of human GIT1 (Q9Y2X7-1).

Isotype: Ig Fraction

Application Details

Application Notes: DB: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for GIT1

Target: GIT1

Alternative Name: GIT1

Background: GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization, increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. It sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes.

Molecular Weight: 84341

Gene ID: 28964

NCBI Accession: NP_001078923, NP_054749

UniProt: Q9Y2X7