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TNK2 antibody (pTyr518)

This anti-TNK2 antibody is a Rabbit Polyclonal antibody detecting TNK2 in DB. Suitable for Human.
Catalog No. ABIN389970

Quick Overview for TNK2 antibody (pTyr518) (ABIN389970)

Target

See all TNK2 Antibodies
TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

Reactivity

  • 119
  • 61
  • 50
  • 3
  • 2
  • 2
Human

Host

  • 115
  • 4
  • 1
Rabbit

Clonality

  • 117
  • 2
Polyclonal

Conjugate

  • 49
  • 8
  • 8
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This TNK2 antibody is un-conjugated

Application

  • 86
  • 54
  • 26
  • 26
  • 22
  • 16
  • 14
  • 11
  • 10
  • 9
  • 6
  • 4
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  • 3
  • 2
  • 1
Dot Blot (DB)

Clone

RB15592
  • Binding Specificity

    • 26
    • 15
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr518

    Predicted Reactivity

    B

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This ACK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y518 of human ACK1.

    Isotype

    Ig Fraction
  • Application Notes

    DB: 1:500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Expiry Date

    6 months
  • Target

    TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

    Alternative Name

    ACK1

    Background

    ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.

    Molecular Weight

    114569

    Gene ID

    10188

    NCBI Accession

    NP_001010938, NP_005772

    UniProt

    Q07912
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