Frataxin antibody (C-Term)

Catalog No. ABIN390377

The Rabbit Polyclonal anti-Frataxin antibody has been validated for WB and IHC (p). It is suitable to detect Frataxin in samples from Human.

Quick Overview for Frataxin antibody (C-Term) (ABIN390377)

Target: Frataxin (FXN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Frataxin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB12571

Product Details anti-Frataxin Antibody

Binding Specificity: AA 143-172, C-Term

Predicted Reactivity: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This FXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the C-terminal region of human FXN.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Frataxin

Target: Frataxin (FXN)

Alternative Name: FXN

Background: FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.

Molecular Weight: 23135

Gene ID: 2395

NCBI Accession: NP_000135, NP_001155178, NP_852090

UniProt: Q16595

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size