ARPC1A antibody (AA 157-184)

Catalog No. ABIN390418

This Rabbit Polyclonal antibody specifically detects ARPC1A in WB, IHC (p) and FACS. It exhibits reactivity toward Human.

Quick Overview for ARPC1A antibody (AA 157-184) (ABIN390418)

Target: ARPC1A (Actin Related Protein 2/3 Complex, Subunit 1A, 41kDa (ARPC1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARPC1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB19554

Product Details anti-ARPC1A Antibody

Binding Specificity: AA 157-184

Predicted Reactivity: X, B, M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ARPC1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-184 amino acids from the Central region of human ARPC1A.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ARPC1A

Target: ARPC1A (Actin Related Protein 2/3 Complex, Subunit 1A, 41kDa (ARPC1A))

Alternative Name: ARPC1A

Background: ARPC1A is one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.

Molecular Weight: 41569

Gene ID: 10552

NCBI Accession: NP_006400

UniProt: Q92747

Pathways: Regulation of Actin Filament Polymerization