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EDNRB antibody (C-Term)

Name: EDNRB antibody (C-Term)
SKU: ABIN390760
Price: 451 USD
Availability: InStock

EDNRB Reactivity: Human, Mouse WB, FACS, IHC (p), IF Host: Rabbit Polyclonal RB19285 unconjugated

Western blot analysis of EDNRB Antibody (C-term) (ABIN390760 and ABIN2841017) in mouse cerebellum tissue lysates (35 μg/lane). (EDNRB antibody (C-Term))

EDNRB Antibody (C-term) (ABIN390760 and ABIN2841017) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. (EDNRB antibody (C-Term))

IHC (p)

Confocal immunofluorescent analysis of EDNRB Antibody (C-term) (ABIN390760 and ABIN2841017) with 293 cell followed by Alexa Fluor®488-conjugated goat anti-rabbit lgG (green). (EDNRB antibody (C-Term))

EDNRB Antibody (C-term) (ABIN390760 and ABIN2841017) flow cytometric analysis of MDA-M cells (bottom histogram) compared to a negative control cell (top histogram). (EDNRB antibody (C-Term))

FACS

4 images

Catalog No. ABIN390760

Datasheet as PDF

Target See all EDNRB Antibodies

EDNRB (Endothelin Receptor Type B (EDNRB))
Binding Specificity
16

15

11

8

7

4

2

2

2

2

2

1

1

1

1

1

1

1

1
AA 409-439, C-Term
Reactivity
81

40

36

10

8

7

7

6

2

1

1

1

1
Human, Mouse
Host
93

8

2

1
Rabbit
Compatible Secondaries
Clonality
94

10
Polyclonal
Conjugate
39

5

4

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2
This EDNRB antibody is un-conjugated
Application
68

24

19

17

14

13

13

12

10

8

3

3

2

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Predicted Reactivity

B, Hs, Pig, Rb, Rat

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This EDNRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-439 amino acids from the C-terminal region of human EDNRB.

Clone

RB19285

Isotype

Ig Fraction
anti-Endothelin Receptor Type B (EDNRB) (AA 31-80) antibody
EDNRB Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-Endothelin Receptor Type B (EDNRB) (AA 27-101) antibody
EDNRB Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-Endothelin Receptor Type B (EDNRB) (C-Term) antibody
EDNRB Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Endothelin Receptor Type B (EDNRB) (N-Term) antibody
EDNRB Reactivity: Human, Dog WB, IHC, IHC (p), ICC Host: Rabbit Polyclonal unconjugated

anti-Endothelin Receptor Type B (EDNRB) (N-Term) antibody
EDNRB Reactivity: Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Endothelin Receptor Type B (EDNRB) (AA 1-100) antibody
EDNRB Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

anti-Endothelin Receptor Type B (EDNRB) (AA 378-442) antibody
EDNRB Reactivity: Mouse, Rat WB, ELISA, FACS Host: Rabbit Polyclonal unconjugated

anti-Endothelin Receptor Type B (EDNRB) antibody
EDNRB Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated

anti-Endothelin Receptor Type B (EDNRB) (C-Term) antibody
EDNRB Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Monkey, Goat, Hamster, Rabbit IHC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Endothelin Receptor Type B (EDNRB) (AA 27-101) antibody
EDNRB Reactivity: Human WB, ELISA Host: Mouse Monoclonal 5H2 unconjugated

Application Notes

IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date

6 months
Target

EDNRB (Endothelin Receptor Type B (EDNRB))

Alternative Name

EDNRB (EDNRB Products)

Background

EDNRB is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene.

Molecular Weight

49644

Gene ID

1910

NCBI Accession

NP_000106, NP_001116131, NP_001188326, NP_003982

UniProt

P24530

Pathways

Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process