ECE1 antibody (AA 392-419)

Catalog No. ABIN390839

The Rabbit Polyclonal anti-ECE1 antibody has been validated for WB. It is suitable to detect ECE1 in samples from Human and Mouse. There is 1 publication available.

Quick Overview for ECE1 antibody (AA 392-419) (ABIN390839)

Target: ECE1 (Endothelin-Converting Enzyme 1 (ECE1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECE1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB20006

Product Details anti-ECE1 Antibody

Binding Specificity: AA 392-419

Predicted Reactivity: B, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ECE-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 392-419 amino acids from the Central region of human ECE-1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-ECE1 antibody (ABIN390839)

Morales-Corraliza, Wong, Mazzella, Che, Lee, Petkova, Wagner, Hemby, Ginsberg, Mathews: "Brain-Wide Insulin Resistance, Tau Phosphorylation Changes, and Hippocampal Neprilysin and Amyloid-β Alterations in a Monkey Model of Type 1 Diabetes." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 36, Issue 15, pp. 4248-58, (2016) (PubMed).

Target Details for ECE1

Target: ECE1 (Endothelin-Converting Enzyme 1 (ECE1))

Alternative Name: ECE-1

Background: ECE-1 is involved in proteolytic processing of endothelin precursors to biologically active peptides.

Molecular Weight: 87164

Gene ID: 1889

NCBI Accession: NP_001106818, NP_001106819, NP_001106820, NP_001388

UniProt: P42892

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling