This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This RGP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids from the C-terminal region of human RGP1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target
RGP1
(RGP1 Retrograde Golgi Transport Homolog (RGP1))
Alternative Name
RGP1
Background
Retrograde golgi transport homolog 1 (RGP1) is the mammalian homolog to the yeast RGP1, and is thought to be a potential Golgi recycling factor. The protein forms a tight complex with RIC1 and this complex binds Ypt6p and stimulates guanine nucleotide exchange. RGP1 yeast mutants exhibit defects in retrograde trafficking that are similar to those seen in yeast, with mutations in other retrograde Golgi transport proteins. It is expected that RGP1 plays a similar role in mammalian cells.