PRPS1,PRPS2,PRPS3 (AA 79-109), (N-Term) antibody
-
- Target
- PRPS1,PRPS2,PRPS3
-
Binding Specificity
- AA 79-109, N-Term
- Reactivity
- Human, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- Un-conjugated
-
Application
- Western Blotting (WB)
- Predicted Reactivity
- B, Pr, Rat, X
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This PRPS1/PRPS2/PRPS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-109 amino acids from the N-terminal region of human PRPS1/PRPS2/PRPS3.
- Clone
- RB5438
- Isotype
- Ig Fraction
-
-
- Application Notes
- WB: 1:1000. WB: 1:1000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
-
-
Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 15, pp. 6223-8, (2007) (PubMed).
: "
-
Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 15, pp. 6223-8, (2007) (PubMed).
-
- Target
- PRPS1,PRPS2,PRPS3
- Alternative Name
- PRPS1/PRPS2/PRPS3
- Background
- Phosphoribosylpyrophosphate synthetase (PRPS, EC 2.7.6.1) catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for the de novo and salvage pathways of purine, pyrimidine, and pyridine biosynthesis. By PCR of human lymphoblast mRNA using primers based on the cDNA sequence of rat PRS I (Prps1), Roessler et al. (1990) isolated a partial human PRPS1 cDNA. They used this partial cDNA to screen lymphoblast cDNA libraries and isolated additional cDNAs corresponding to the entire PRPS1 coding region. The deduced PRPS1 protein has 318 amino acids.
- Molecular Weight
- 34834
- Gene ID
- 5631
- NCBI Accession
- NP_001191331, NP_002755
- UniProt
- P60891
-