This anti-AMHR2 antibody is a Rabbit Polyclonal antibody detecting AMHR2 in WB. Suitable for Human. This Primary Antibody has been cited in 3+ publications.
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This AMHR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human AMHR2.
Verified
AMHR2
Reactivity: Human
WB, ELISA
Host: Goat
Polyclonal
unconjugated
Application Notes
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Almeida, Conley, Ball: "Expression of anti-Müllerian hormone, CDKN1B, connexin 43, androgen receptor and steroidogenic enzymes in the equine cryptorchid testis." in: Equine veterinary journal, Vol. 45, Issue 5, pp. 538-45, (2013) (PubMed).
Almeida, Conley, Mathewson, Ball: "Expression of anti-Müllerian hormone, cyclin-dependent kinase inhibitor (CDKN1B), androgen receptor, and connexin 43 in equine testes during puberty." in: Theriogenology, Vol. 77, Issue 5, pp. 847-57, (2012) (PubMed).
Almeida, Ball, Conley, Place, Liu, Scholtz, Mathewson, Stanley, Moeller: "Biological and clinical significance of anti-Müllerian hormone determination in blood serum of the mare." in: Theriogenology, Vol. 76, Issue 8, pp. 1393-403, (2011) (PubMed).
Target
AMHR2
(Anti-Mullerian Hormone Receptor, Type II (AMHR2))
Alternative Name
AMHR2
Target Type
Antibody
Background
The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth, anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.