COL4A1 antibody (N-Term)

Catalog No. ABIN391551

Product Details anti-COL4A1 Antibody

Target: COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))

Binding Specificity: AA 27-54, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL4A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This COL4A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-54 amino acids from the N-terminal region of human COL4A1.

Clone: RB19425

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:25. WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-COL4A1 antibody (ABIN391551)

Chou, Chuang, Lu, Guh: "Vitamin D-binding protein is required for the protective effects of vitamin D in renal fibroblasts and is phosphorylated in diabetic rats." in: Molecular and cellular endocrinology, Vol. 411, pp. 67-74, (2015) (PubMed).

Tiao, Wang, Huang, Chuang, Kuo, Yang, Huang: "MicroRNA-29a protects against acute liver injury in a mouse model of obstructive jaundice via inhibition of the extrinsic apoptosis pathway." in: Apoptosis : an international journal on programmed cell death, Vol. 19, Issue 1, pp. 30-41, (2014) (PubMed).

Yao, Yang, Liu, Tan, Lu, Yuan, Ma: "Follicle-stimulating hormone regulation of microRNA expression on progesterone production in cultured rat granulosa cells." in: Endocrine, Vol. 38, Issue 2, pp. 158-66, (2010) (PubMed).

Target Details for COL4A1

Target: COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))

Alternative Name: COL4A1 (COL4A1 Products)

Background: COL4A1 is the major type IV alpha collagen chain of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter.

Molecular Weight: 160611

Gene ID: 1282

NCBI Accession: NP_001836

UniProt: P02462

Pathways: Skeletal Muscle Fiber Development, Growth Factor Binding