Cytokeratin 18 antibody (C-Term)

Catalog No. ABIN2841501

This Rabbit Polyclonal antibody specifically detects Cytokeratin 18 in WB, IF, FACS and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for Cytokeratin 18 antibody (C-Term) (ABIN2841501)

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytokeratin 18 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB18746

Product Details anti-Cytokeratin 18 Antibody

Binding Specificity: AA 401-430, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CYK18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the C-terminal region of human CYK18.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. IF: 1:25. IF: 1:25. IF: 1:25. WB: 1:2000. WB: 1:2000. WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Cytokeratin 18

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Alternative Name: CYK18

Background: KRT18 is the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament family. They are expressed in single layer epithelial tissues of the body. Mutations in its gene have been linked to cryptogenic cirrhosis.

Molecular Weight: 48058

Gene ID: 3875

NCBI Accession: NP_000215, NP_954657

UniProt: P05783

Pathways: Apoptosis, Caspase Cascade in Apoptosis