Casein Kinase 1 delta antibody (C-Term)
Quick Overview for Casein Kinase 1 delta antibody (C-Term) (ABIN391599)
Target
See all Casein Kinase 1 delta (CSNK1D) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 321-352, C-Term
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Predicted Reactivity
- B, M, Rat
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This CSNK1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-352 amino acids from the C-terminal region of human CSNK1D.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000. IHC-P: 1:50~100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Expiry Date
- 6 months
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- Casein Kinase 1 delta (CSNK1D) (Casein Kinase 1, delta (CSNK1D))
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Alternative Name
- Casein Kinase 1 delta (CK1D)
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Background
- Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The casein kinase 1 (CK1) group consists of 12 kinases including CK1, TTBK (tau tubulin kinase), and VRK (vaccinia-related kinase) families. The receptor guanylate cyclase (RGC) group consists of 5 kinases similar in domain sequence to TKs (ANP, CYG).
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Molecular Weight
- 47330
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Gene ID
- 1453
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NCBI Accession
- NP_001884, NP_620693
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UniProt
- P48730
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Pathways
- Hedgehog Signaling, M Phase
Target
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