Casein Kinase 1 gamma 2 antibody (C-Term)

Catalog No. ABIN391602

This anti-Casein Kinase 1 gamma 2 antibody is a Rabbit Polyclonal antibody detecting Casein Kinase 1 gamma 2 in WB and IHC (p). Suitable for Human.

Quick Overview for Casein Kinase 1 gamma 2 antibody (C-Term) (ABIN391602)

Target: Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Casein Kinase 1 gamma 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB0852

Product Details anti-Casein Kinase 1 gamma 2 Antibody

Binding Specificity: AA 329-360, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CSNK1G2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-360 amino acids from the C-terminal region of human CSNK1G2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Casein Kinase 1 gamma 2

Target: Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))

Alternative Name: Casein Kinase 1 gamma 2 (CK1G2)

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The casein kinase 1 (CK1) group consists of 12 kinases including CK1, TTBK (tau tubulin kinase), and VRK (vaccinia-related kinase) families. The receptor guanylate cyclase (RGC) group consists of 5 kinases similar in domain sequence to TKs (ANP, CYG).

Molecular Weight: 47457

Gene ID: 1455

NCBI Accession: NP_001310

UniProt: P78368

Pathways: Hedgehog Signaling