LTBP1 antibody (C-Term)

Catalog No. ABIN392207

There is 1 publication for this product available. The Rabbit Polyclonal anti-LTBP1 antibody is suitable to detect LTBP1 in samples from Mouse and Human. It has been validated for WB and IHC (p).

Quick Overview for LTBP1 antibody (C-Term) (ABIN392207)

Target: LTBP1 (Latent Transforming Growth Factor beta Binding Protein 1 (LTBP1))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB14971

Product Details anti-LTBP1 Antibody

Binding Specificity: AA 1493-1525, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This LTBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1493-1525 amino acids from the C-terminal region of human LTBP1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-LTBP1 antibody (ABIN392207)

Saraon, Musrap, Cretu, Karagiannis, Batruch, Smith, Drabovich, Trudel, van der Kwast, Morrissey, Jarvi, Diamandis: "Proteomic profiling of androgen-independent prostate cancer cell lines reveals a role for protein S during the development of high grade and castration-resistant prostate cancer." in: The Journal of biological chemistry, Vol. 287, Issue 41, pp. 34019-31, (2012) (PubMed).

Target Details for LTBP1

Target: LTBP1 (Latent Transforming Growth Factor beta Binding Protein 1 (LTBP1))

Alternative Name: LTBP1

Background: LTBP1 may be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. This protein may play critical roles in controlling and directing the activity of TGFB1, and it may have a structural role in the extra cellular matrix (ECM).

Molecular Weight: 186796

Gene ID: 4052

NCBI Accession: NP_000618, NP_001159736, NP_001159737, NP_001159738, NP_996826

UniProt: Q14766

Pathways: Maintenance of Protein Location, Growth Factor Binding