ALDH3A1 antibody (AA 254-284)

Catalog No. ABIN392319

This anti-ALDH3A1 antibody is a Rabbit Polyclonal antibody detecting ALDH3A1 in WB and IHC (p). Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for ALDH3A1 antibody (AA 254-284) (ABIN392319)

Target: ALDH3A1 (Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH3A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB16832

Product Details anti-ALDH3A1 Antibody

Binding Specificity: AA 254-284

Predicted Reactivity: B

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ALDH3A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-284 amino acids from the Central region of human ALDH3A1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-ALDH3A1 antibody (ABIN392319)

Voulgaridou, Kiziridou, Mantso, Chlichlia, Galanis, Koukourakis, Franco, Panayiotidis, Pappa: "Aldehyde dehydrogenase 3A1 promotes multi-modality resistance and alters gene expression profile in human breast adenocarcinoma MCF-7 cells." in: The international journal of biochemistry & cell biology, Vol. 77, Issue Pt A, pp. 120-128, (2017) (PubMed).

Target Details for ALDH3A1

Target: ALDH3A1 (Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1))

Alternative Name: ALDH3A1

Background: Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. ALDH3A1 forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. The enzyme is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea.

Molecular Weight: 50395

Gene ID: 218

NCBI Accession: NP_000682, NP_001128639, NP_001128640

UniProt: P30838