MAP3K14 antibody (AA 119-148)

Catalog No. ABIN392496

The Rabbit Polyclonal anti-MAP3K14 antibody (Clone RB3337) (ABIN392496) specifically detects MAP3K14 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for MAP3K14 antibody (AA 119-148) (ABIN392496)

Target: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K14 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB3337

Product Details anti-MAP3K14 Antibody

Binding Specificity: AA 119-148

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NIK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of human NIK.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for MAP3K14

Target: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Alternative Name: NIK

Background: NIK (mitogen-activated protein kinase kinase kinase 14), a member of the Ser/Thr protein kinase family, binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.

Molecular Weight: 104042

Gene ID: 9020

NCBI Accession: NP_003945

UniProt: Q99558

Pathways: NF-kappaB Signaling, TCR Signaling