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14-3-3 zeta antibody (AA 211-239)

The Rabbit Polyclonal anti-14-3-3 zeta antibody has been validated for WB and IHC (p). It is suitable to detect 14-3-3 zeta in samples from Human.
Catalog No. ABIN392783

Quick Overview for 14-3-3 zeta antibody (AA 211-239) (ABIN392783)

Target

See all 14-3-3 zeta (YWHAZ) Antibodies
14-3-3 zeta (YWHAZ)

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This 14-3-3 zeta antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB7161
  • Binding Specificity

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    AA 211-239

    Predicted Reactivity

    B, C, M, Rat, Sh

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This YWHAZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-239 amino acids from human YWHAZ.

    Isotype

    Ig Fraction
  • Application Notes

    WB: 1:1000. IHC-P: 1:10~50

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Expiry Date

    6 months
  • Target

    14-3-3 zeta (YWHAZ)

    Alternative Name

    14-3-3 protein zeta/delta

    Background

    14-3-3 protein zeta/delta belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and sheep orthologs.

    Molecular Weight

    27745

    Gene ID

    7534

    NCBI Accession

    NP_001129171, NP_001129172, NP_001129173, NP_001129174, NP_003397, NP_663723

    UniProt

    P63104

    Pathways

    Apoptosis, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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