ITPKA antibody (C-Term)

Catalog No. ABIN392800

This Rabbit Polyclonal antibody specifically detects ITPKA in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for ITPKA antibody (C-Term) (ABIN392800)

Target: ITPKA (Inositol-Trisphosphate 3-Kinase A (ITPKA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITPKA antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB5359

Product Details anti-ITPKA Antibody

Binding Specificity: AA 345-375, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ITPKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-375 amino acids from the C-terminal region of human ITPKA.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ITPKA

Target: ITPKA (Inositol-Trisphosphate 3-Kinase A (ITPKA))

Alternative Name: ITPKA

Background: ITPKA regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68 % identical in the C-terminus region.

Molecular Weight: 51009

Gene ID: 3706

NCBI Accession: NP_002211

UniProt: P23677