Galectin 3 antibody (Biotin)
Quick Overview for Galectin 3 antibody (Biotin) (ABIN393010)
Target
See all Galectin 3 (LGALS3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
 - The antibody recognizes a 32,000 dalton surface antigen found on a subpopulation of mouse macrophages. It reactswith peritoneal exudate macrophages where the exudate is provoked by thioglycollate, protease peptone (20 % ),macrophages of lymphoid and non-lymphoid tissues, interdigitating dendritic cells and Langerhans cells. Mac-2 isalso expressed in the cytoplasm on non-elicited resident macrophages, 5 % are strongly reactive, the remaining 95 %show much weaker staining.The antibody does not react with peritoneal exudate macrophages where the exudate is provoked by Listeriamonocytogenes, lipopolysaccharide or concanavalin A. It also does not react with peritoneal macrophages, splenicmacrophages, granulocytes, thymocytes, peripheral lymph node cells and with 99 % of bone marrow cells.
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Purification
 - Protein G purified
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Immunogen
 - Plasma membrane glycoproteins from C57BL/6 mouse thioglycollate-elicited peritoneal exudate.
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Isotype
 - IgG2a
 
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Application Notes
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                        Approved: ELISA, Flo (0.5 μg/10 x106), IHC, IHC-Fr, IHC-P (1:1000 - 1:2000)
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - 
                                            
Comment
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Target Species of Antibody: Mouse
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Restrictions
 - For Research Use only
 
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Format
 - Liquid
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Concentration
 - Lot specific
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Buffer
 - PBS, 0.02 % sodium azide, EIA grade BSA.
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Preservative
 - Sodium azide
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Precaution of Use
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
 - 4 °C,-20 °C
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Storage Comment
 - Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
 
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- Galectin 3 (LGALS3)
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Alternative Name
 - MAC-2 / Galectin 3
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Target Type
 - Chemical
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Background
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                        Name/Gene ID: LGALS3
Synonyms: LGALS3, 35 kd lectin, 35 kDa lectin, CBP35, GAL3, Galactoside-binding protein, GALIG, IgE-binding protein, Laminin-binding protein, Gal-3, GALBP, MAC-2, Mac-2 antigen, L31, MAC2, CBP 35, Galactose-specific lectin 3, Galectin-3, L-31, Lectin L-29 - 
                                            
Gene ID
 - 3958
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UniProt
 - P17931
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Pathways
 - RTK Signaling
 
Target
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