CMV Glycoprotein B (CMV gB) antibody
Quick Overview for CMV Glycoprotein B (CMV gB) antibody (ABIN393151)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Detects cytomegalovirus glycoprotein B late cytoplasmic antigen. Cytomegalovirus is an enveloped double stranded DNA virus which in humans (HCMV) is commonly known as human herpesvirus 5 (HHV-5). Glycoprotein B (gB) is the main antigenic protein within the envelope of HCMV. It is required for HCMV mediated membrane fusion along with the gH / gL complex. The unprocessed precursor of HCMV gB is 906 amino acids in length, with a MW of approximately 100kD. Does not react with HSV, VZV or EBV. Reacts with MRC-5 infected cells, but not uninfected cells. Has been used successfully to demonstrate presence of CMV in infected cells by immunofluorescence on paraformaldehyde fixed cell cultures.
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Purification
- Affinity purified
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Immunogen
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Native.
Type of Immunogen: Native protein -
Isotype
- IgG2a
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Application Notes
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Approved: ELISA, IF, IHC, IHC-Fr
Usage: Immunohistology: Reactive only in acetone fixed CMV infected cells or frozen sections. -
Comment
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Target Species of Antibody: Cytomegalovirus
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
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Short term: -20°C
Long term: -20°C.
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- CMV Glycoprotein B (CMV gB)
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Target Type
- Viral Protein
Target
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