Glucose-6-Phosphate Dehydrogenase antibody (AA 35-506)

Catalog No. ABIN400862

The Mouse Monoclonal anti-Glucose-6-Phosphate Dehydrogenase antibody has been validated for WB, IHC (p) and EIA. It is suitable to detect Glucose-6-Phosphate Dehydrogenase in samples from Human.

Quick Overview for Glucose-6-Phosphate Dehydrogenase antibody (AA 35-506) (ABIN400862)

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Glucose-6-Phosphate Dehydrogenase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: AT2F6

Product Details anti-Glucose-6-Phosphate Dehydrogenase Antibody

Binding Specificity: AA 35-506

Specificity: The antibody recognizes human G6PD. Other species not tested.

Characteristics: Synonyms: Glucose-6-phosphate 1-dehydrogenase, Glucose-6-P-Dehydrogenase

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human G6PD (35-506 aa) purified from E. coli

Isotype: IgG2b

Application Details

Application Notes: ELISA. Western blot (1: 1,000 - 1: 2,000). Immunohistochemistry on Paraffin Sections (5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Glucose-6-Phosphate Dehydrogenase

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Alternative Name: G6PD

Background: Glucose-6-phosphate dehydrogenase (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells by maintaining the level of NADPH. G6PD converts glucose-6-phosphate into 6-phosphoglucono-δ-lactone and simultaneously produce NADPH. The NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. G6PD deficiency cause acute hemolytic anemia.Synonyms: Glucose-6-P-Dehydrogenase, Glucose-6-phosphate 1-dehydrogenase

Gene ID: 2539

UniProt: P11413

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones