CASZ1 antibody (N-Term)

Catalog No. ABIN401359

This Rabbit Polyclonal antibody specifically detects CASZ1 in WB and EIA. It exhibits reactivity toward Human, Mouse, Rat, Cow and Chimpanzee.

Quick Overview for CASZ1 antibody (N-Term) (ABIN401359)

Target: CASZ1 (Castor Zinc Finger 1 (CASZ1))

Reactivity: Human, Mouse, Rat, Cow, Chimpanzee

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASZ1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-CASZ1 Antibody

Binding Specificity: N-Term

Specificity: This antibody is directed against Cas5 protein.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Chimpanzee, Bovine, Rat.
Species reactivity (tested):Human.

Purification: Affinity Purified

Immunogen: Synthetic peptide corresponding to region near the amino terminal end of human Cas5 protein

Isotype: IgG

Application Details

Application Notes: ELISA: 1/25,000 - 1/100,000. Western blot: 1/1,000 - 1/3,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.3 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for CASZ1

Target: CASZ1 (Castor Zinc Finger 1 (CASZ1))

Alternative Name: CASZ1

Background: HCas5 (Castor) is the human homolog of a Drosophila gene that regulates neurogenesis. In human neuroblastoma tumors where a loss of heterozygosity of CASZ1 is noted, hCas functions to suppress the tumorigenicity of cells. hCas5 is a developmentally regulated transcription factor found in neural and muscle cells. hCas5 is a Zn finger transcription factor that is predominantly found in the nucleus. This antibody is designed to facilitate the functional study of this protein and its role in developmental regulation and expression in human tumor tissues.Synonyms: CST, Castor-related protein, Putative survival-related protein, SRG, ZNF693, Zinc finger protein 693, Zinc finger protein castor homolog 1

Gene ID: 54897

NCBI Accession: NP_001073312

UniProt: Q86V15