14-3-3 zeta antibody (Internal Region, pSer184)

Catalog No. ABIN410146

This Rabbit Polyclonal antibody specifically detects 14-3-3 zeta in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for 14-3-3 zeta antibody (Internal Region, pSer184) (ABIN410146)

Target: 14-3-3 zeta (YWHAZ)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 14-3-3 zeta antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-14-3-3 zeta Antibody

Binding Specificity: Internal Region, pSer184

Specificity: Reacts with human 28 kDa KCIP-1/pS184 phosphorylated protein

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): May cross reacts with proteins from mouse, rat and other species due to sequences homology.

Purification: Antiserum

Immunogen: Synthetic peptide derived from internal domain of the human KCIP-1 protein containing phosphoserine at position 184.

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/50 to 1/200 - WB : 1/100 to 1/1 000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for 14-3-3 zeta

Target: 14-3-3 zeta (YWHAZ)

Alternative Name: 14-3-3 Protein zeta/delta

Background: Belongs to the 14-3-3 family. Interacts with CDK16 and BSPRY, WEE1 (C-terminal), SAMSN1, MLF1 (phosphorylated form), Thr-phosphorylated ITGB2, BCL2L11, FOXO4, NOXA1, SSH1 and ARHGEF2.

Gene ID: 7534

UniProt: P63104

Pathways: Apoptosis, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location