Coagulation Factor IX antibody

Catalog No. ABIN452591

The Mouse Monoclonal anti-Coagulation Factor IX antibody has been validated for EIA. It is suitable to detect Coagulation Factor IX in samples from Human.

Quick Overview for Coagulation Factor IX antibody (ABIN452591)

Target: Coagulation Factor IX (F9)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Coagulation Factor IX antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Clone: F9-1

Product Details anti-Coagulation Factor IX Antibody

Specificity: Human Factor IX.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Characteristics: Synonyms: Christmas factor, PTC, Plasma thromboplastin component

Purification: Affinity Chromatography on Protein G.

Immunogen: Human Factor IX.

Isotype: IgG1

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with Double distillated water to a final concentration of 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.2 without preservatives.

Preservative: Without preservative

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Coagulation Factor IX

Target: Coagulation Factor IX (F9)

Background: Factor IX circulates in the blood as an inactive zymogen at the normal concentration of approximately 3 μg/mL. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca2+ ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X linked disorder, also called hemophilia B or Christmas disease. The disease affects approximately 1 in 50,000 of the population (almost exclusively males).Synonyms: Christmas factor, PTC, Plasma thromboplastin component

Gene ID: 2158

UniProt: P00740