Coagulation Factor IX antibody (AA 266-295)

Catalog No. ABIN1538212

This Rabbit Polyclonal antibody specifically detects Coagulation Factor IX in WB. It exhibits reactivity toward Human.

Quick Overview for Coagulation Factor IX antibody (AA 266-295) (ABIN1538212)

Target: Coagulation Factor IX (F9)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Coagulation Factor IX antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB36658

Product Details anti-Coagulation Factor IX Antibody

Binding Specificity: AA 266-295

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This F9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-295 amino acids from the Central region of human F9.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: F9 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for Coagulation Factor IX

Target: Coagulation Factor IX (F9)

Alternative Name: F9

Background: This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.

Molecular Weight: 51778

Gene ID: 2158

NCBI Accession: NP_000124

UniProt: P00740