PROC antibody

Catalog No. ABIN452606

The Mouse Monoclonal anti-PROC antibody has been validated for EIA. It is suitable to detect PROC in samples from Human.

Quick Overview for PROC antibody (ABIN452606)

Target: PROC (Vitamin K-dependent protein C (PROC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PROC antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Clone: HLW-C

Product Details anti-PROC Antibody

Specificity: Human Protein C.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Characteristics: Synonyms: Vitamin K-dependent protein C, PROC, Autoprothrombin IIA, Anticoagulant protein C, Bloodcoagulation factor XIV

Purification: Affinity Chromatography on Protein G.

Immunogen: Human Protein C derived from Human blood.

Isotype: IgG2b

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.2 without preservatives.

Preservative: Without preservative

Storage: -20 °C

Storage Comment: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for PROC

Target: PROC (Vitamin K-dependent protein C (PROC))

Alternative Name: Protein C / PROC

Background: Protein C is a vitamin K dependent serine protease zymogen. Purified human activated protein C selectively destroys factors Va and VIII:C in human plasma and thus has an important anticoagulant role. Protein C deficiency has been associated with inherited thrombophilia. In its primary structure, protein C is similar to the prothrombin group of blood coagulation factors. It most closely resembles factor X. Protein C is synthesized as a single chain, this precursor molecule is cleaved into a light chain and a heavy chain held together by a disulfide bond. The enzyme is then activated by thrombin, which cleaves a tetradecapeptide from the amino end of the heavy chain.Synonyms: Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV, Inactivator of coagulation factors Va and VIIIa, PROC1, Vitamin K-dependent protein C

Gene ID: 5624

UniProt: P04070