Growth Hormone 1 antibody (Biotin)

Catalog No. ABIN452627

The Mouse Monoclonal anti-Growth Hormone 1 antibody has been validated for EIA. It is suitable to detect Growth Hormone 1 in samples from Human.

Quick Overview for Growth Hormone 1 antibody (Biotin) (ABIN452627)

Target: Growth Hormone 1 (GH1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Growth Hormone 1 antibody is conjugated to Biotin

Application: Enzyme Immunoassay (EIA)

Clone: YC8

Product Details anti-Growth Hormone 1 Antibody (Biotin)

Specificity: This monoclonal antibody reacts with natural and recombinant hGH.Aff. Const.:1.7 x 1010/M measured by Friguet's (1985) method

Characteristics: Synonyms: Pituitary growth hormone, Growth hormone 1, HGH

Purification: Affinity Chromatography on Protein G

Immunogen: Purified Recombinant hGH

Isotype: IgG1

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01 M PBS, pH 7.2, 0.1 % Proclin-300, 1 % Gelatin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Growth Hormone 1

Target: Growth Hormone 1 (GH1)

Alternative Name: Somatotropin / Growth Hormone / GH1

Background: Human growth hormone (hGH) plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. The effects of hGH in the body can be generally described as anabolic. It stimulates amino acid uptake and protein synthesis in muscle and other tissues. Growth Hormone (GH1) is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Genes for growth hormone (GH) are found in a gene cluster on 17q, which consists of two growth hormone genes and three CSH genes. The GHN1 gene is transcribed exclusively in the pituitary, whereas the other 4 genes are expressed only in placental tissues. Several isoforms of GH1 exist.Synonyms: Growth hormone 1, HGH, Pituitary growth hormone

Gene ID: 2688

UniProt: P01241

Pathways: NF-kappaB Signaling, JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process