Dermcidin antibody (C-Term)
Quick Overview for Dermcidin antibody (C-Term) (ABIN452901)
Target
See all Dermcidin (DCD) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Specificity
- This antibody detects DCD at C-term.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human
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Purification
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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Immunogen
- KLH conjugated synthetic peptide selected from the C-terminal region of human DCD
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Application Notes
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Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- Dermcidin (DCD)
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Alternative Name
- Dermcidin
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Background
- DCD is a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients.Synonyms: AIDD, DCD, DSEP, Preproteolysin
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Molecular Weight
- 11284 Da
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Gene ID
- 117159
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NCBI Accession
- NP_444513
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UniProt
- P81605
Target
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