SERPINC1 antibody (C-Term)

Catalog No. ABIN453366

The Rabbit Polyclonal anti-SERPINC1 antibody (ABIN453366) specifically detects SERPINC1 in WB and EIA. The antibody is reactive with Human and Mouse samples.

Quick Overview for SERPINC1 antibody (C-Term) (ABIN453366)

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINC1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SERPINC1 Antibody

Binding Specificity: C-Term

Specificity: Detects Antithrombin III (C-term).

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Antithrombin III antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of Human Antithrombin III.

Application Details

Application Notes: ELISA: 1/1,000Western blotting: 1/50approx. 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C or (in aliquots) at -20 °C for longer.

Target Details for SERPINC1

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Alternative Name: SERPINC1 / Antithrombin-III

Background: Antithrombin III (ATH III) is a plasma protein synthesised in the liver. Normal plasma levels are 115 to 160 mg/L. ATH III consists of a single polypeptide chain and has a molecular weight of 58 kDa. ATH III is a serine protease inhibitor and regulates coagulation by the formation of covalently liked complexes. ATH III also has a heparin binding site and in the presence of heparin the inhibition of thrombin, factors IXa, Xa and XIa is enhanced 1000 fold. Low levels of ATH III (functional or concentration) are associated with deep vein thrombosis and pulmonary embolism. Antithrombin assays are based on immunologic, enzymatic, or clotting properties.Synonyms: AT3, ATIII, Serpin C1

Gene ID: 462

NCBI Accession: NP_000479

UniProt: P01008