TYR antibody (C-Term)

Catalog No. ABIN453446

The Rabbit Polyclonal anti-TYR antibody has been validated for WB, IF, FACS, IHC (p) and EIA. It is suitable to detect TYR in samples from Human.

Quick Overview for TYR antibody (C-Term) (ABIN453446)

Target: TYR (Tyrosinase (TYR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYR antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-TYR Antibody

Binding Specificity: C-Term

Specificity: This antibody recognizes Human Tyrosinase (TYR). Other species not tested.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human TYR

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TYR

Target: TYR (Tyrosinase (TYR))

Background: TYR catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The protein has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this protein result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation.Synonyms: LB24-AB, Monophenol monooxygenase, SK29-AB, Tumor rejection antigen AB

Molecular Weight: 60393 Da

Gene ID: 7299

NCBI Accession: NP_000363

UniProt: P14679