Annexin VII antibody (Middle Region)

Catalog No. ABIN453514

This Rabbit Polyclonal antibody specifically detects Annexin VII in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for Annexin VII antibody (Middle Region) (ABIN453514)

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin VII antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Annexin VII Antibody

Binding Specificity: Middle Region

Specificity: This antibody reacts to Annexin A7 (ANXA7).

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human ANXA7

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Annexin VII

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Alternative Name: Annexin A7 / ANXA7

Background: Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. ANXA7 is a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.Synonyms: ANX7, Annexin VII, Annexin-7, SNX, Synexin

Gene ID: 310

NCBI Accession: NP_001147

UniProt: P20073