CTPS2 antibody (N-Term)

Catalog No. ABIN453590

The Rabbit Polyclonal anti-CTPS2 antibody has been validated for WB and EIA. It is suitable to detect CTPS2 in samples from Human.

Quick Overview for CTPS2 antibody (N-Term) (ABIN453590)

Target: CTPS2 (CTP Synthase II (CTPS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTPS2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-CTPS2 Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to CTPS2.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the N-term region of human CTPS2

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CTPS2

Target: CTPS2 (CTP Synthase II (CTPS2))

Alternative Name: CTP Synthase 2

Background: CTPS2 catalyzes the formation of CTP from UTP with the concomitant eamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy.Synonyms: CTP synthetase 2, CTPS2, UTP-ammonia ligase 2

Gene ID: 56474

NCBI Accession: NP_001137474

UniProt: Q9NRF8

Pathways: Ribonucleoside Biosynthetic Process