ESRRA antibody (Middle Region)

Catalog No. ABIN453642

This anti-ESRRA antibody is a Rabbit Polyclonal antibody detecting ESRRA in WB and EIA. Suitable for Human.

Quick Overview for ESRRA antibody (Middle Region) (ABIN453642)

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESRRA antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ESRRA Antibody

Binding Specificity: Middle Region

Specificity: This antibody reacts to ESRRA.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human ESRRA

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Alternative Name: Estrogen-Related Receptor alpha

Background: ESRRA is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes.Synonyms: ERR1, ESRL1, ESRRA, Estrogen receptor-like 1, NR3B1, Nuclear receptor subfamily 3 group B member 1, Steroid hormone receptor ERR1

Gene ID: 2101

NCBI Accession: NP_004442

UniProt: P11474

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha