FLCN antibody (Middle Region)

Catalog No. ABIN453652

This Rabbit Polyclonal antibody specifically detects FLCN in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for FLCN antibody (Middle Region) (ABIN453652)

Target: FLCN (Folliculin (FLCN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLCN antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-FLCN Antibody

Binding Specificity: Middle Region

Specificity: This antibody reacts to FLCN.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human FLCN

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FLCN

Target: FLCN (Folliculin (FLCN))

Alternative Name: Folliculin

Target Type: Amino Acid

Background: FLCN may play a role in the pathogenesis of an uncommon form of kidney cancer through its association with an inherited disorder of the hair follicle (fibrofolliculomas). FLCN may be a tumor suppressor. May be involved in colorectal tumorigenesis. It may be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways.Synonyms: BHD, BHD skin lesion fibrofolliculoma protein, Birt-Hogg-Dube syndrome protein, FLCN

Gene ID: 201163

NCBI Accession: NP_653207

UniProt: Q8NFG4

Pathways: Cell-Cell Junction Organization