CCL7 antibody (HRP)

Catalog No. ABIN453920

The Mouse Monoclonal anti-CCL7 antibody has been validated for EIA. It is suitable to detect CCL7 in samples from Human.

Quick Overview for CCL7 antibody (HRP) (ABIN453920)

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCL7 antibody is conjugated to HRP

Application: Enzyme Immunoassay (EIA)

Clone: 113

Product Details anti-CCL7 Antibody (HRP)

Specificity: Reactive with natural and recombinant human MCP-3. Does not show any cross reaction with other Human Cytokines or growth factors tested such as IL1 beta, IL-8, MCAF, SAA and EGF

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein G.

Immunogen: Purified Recombinant Human Monocyte Chemotactic Protein-3 (MCP-3).

Isotype: IgG1

Application Details

Application Notes: ELISA: This MCP3 antibody HRP-conjugated can be used as a Tracer/Detection Antibody inSandwich ELISA applications for human MCP-3 detection in combination with a Captureantibody (Cat#DM2039)Suggested Capture Coating Dose: 3 μg/wellSubstrate: TMB
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01 M PBS, pH 7.0 ± 0.1 in 50 % Glycerol and 0.01 % Thimerosal as a bacteriostat

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody at 2 - 8 °C. DO NOT FREEZE!

Target Details for CCL7

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Alternative Name: MCP3 / CCL7

Background: Macrophage/monocyte chemotactic protein-3 (MCP-3), like other two closely related chemokines (MCP1 and MCP-2), is chemotactic to monocytes, but not to neutrophils. MCP-3 showed 78 % sequence homology with MCP-1 and 58 % sequence homology with MCP-2. The primary receptor for MCP-3 is D6. MCP-3 also competes with MCP-1 to bind to CCR10, and competes with Rantes and MIP-1α to bind to CCR1. MCP-3 stimulates macrophage to secrete proteases. A variety of cancer cell lines express MCP-3, suggesting a role in tumor invasion and metastasia.Synonyms: C-C motif chemokine 7, CCL-7, MCP-3, Macrophage Chemotactic Protein-3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, SCYA6, SCYA7, Small-inducible cytokine A7

Gene ID: 6354

NCBI Accession: NP_006264

UniProt: P80098